Theracurmin® — Our unique form of curcumin with markedly improved absorptivity.
Curcumin is relatively insoluble in water. When orally ingested, most of the curcumin is excreted without being absorbed in the small intestine. It is clear that, to obtain maximum benefits, it is most important to improve the body’s systemic absorption of the ingested curcumin.
Theracurmin® is an innovative curcumin formulation featuring dramatically enhanced absorption and bioavailability. Developed using our fine granulation and suspension technology, Theracurmin® is in the form of sub-micron particles that are stabilized when dispersed in water.
Human clinical study demonstrates increased absorption
Theracurmin® Compared to Ordinary Curcumin Powder Plasma Curcumin Level
AUC 0-6 hrs
Seven healthy adult men and women ingested a single dose (30 mg) of curcumin as ordinary curcumin powder or Theracurmin®. Blood was collected over time at 1-6 hours after ingestion to determine blood curcumin levels. The trial confirmed Theracurmin® results in 27 times higher bioavailability when compared to ordinary curcumin powder.
Theracurmin® Compared to Competitors’ Products Plasma Curcumin Level
AUC 0-6 hrs per 1mg curcumin
Nine healthy adult men and women ingested a single dose of Theracurmin®, Product M and Product B under randomized controlled cross-over trial. Blood was collected over time at 1-6 hours after ingestion to determine plasma curcumin levels. The trial confirmed Theracurmin® results in 4 times and 18 times higher bioavailability when compared to Product M and Product.
Highly stable within most manufacturing processes and conditions
Theracurmin® Stability When Dispersed in Water
Because of our unique technology, Theracurmin® is stably dispersed and dissolved in water and can easily be used in beverages.
Theracurmin® Stability When Exposed to Light
Theracurmin® proved stable in a light irradiation test. Theracurmin® is compatible with transparent containers, such as PET bottles.
Theracurmin® Stability When Exposed to Heat
Theracurmin® proved stable in a heat resistance test at 95C and 120C. No change was noted in the residual ratio of curcumin. Theracurmin® can be used under pasteurization conditions for beverages and food.
Theracurmin® is safe for human use.
Study results for oral dosage and the safety of curcumin have shown:
• No toxicity was found after acute toxicity test (administration of 2,000 mg/kg of curcumin), sub-acute toxicity test (1,000 mg/kg/day for 2 weeks) and repeated dose toxicity test (100mg/kg/day for 90 days).
• Negative mutagenicity test
Theracurmin® — Summary of Key Features.
• Markedly improved biological absorption
• Equivalent or higher absorptivity with approx. 1/30 the dosage of conventional products
• Easily dispersible in water with almost no precipitation
• Brilliant yellow color
• Almost no taste or smell
• Excellent light and heat resistance
• Readily washable production line
• Applicable to various products regardless of their forms